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Sep 2015
1 year later

I have a Makerbot Replicator 2x at my school that I “converted” to run with Slic3r instead of the stock Makerbot Desktop. My print quality has gone up exponentially with this upgrade and I’m actually using the stock Prusa i3 version of Slic3r! What you have to do in order to use the slicer is run the gcode through a converter to format the gcode to .x3g (which is what the replicator 2x needs). To do this I downloaded a converter from kpn3d (https://knp3d.com/software/#knp3dconverter 258). Next, in the post-processing script in the slicer software you copy and past the location of the converter. It should look something like this C:\Users\Thomas\Google Drive\MAKERBOT REPLICATOR 2X\SOFTWARE\GCODE TO X3G\knp3d\KnP3D+Converter.exe. This will run the sliced file (gcode) through the converter and give you an .x3g file to send to your printer (I use an sd card). This adds steps to the printing process but it is worth it because you can use whatever slicer you want. Also, there are some slicing software out there that can export different formats right away. I think Simplify3d can do this. Good luck and hope this helped!